Investigation of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio Parameters in Chronic Gastritis with Helicobacter Pylori

INTRODUCTION: Easily accessible parameters are needed to predict the presence of Helicobacter pylori (HP) and to decide on endoscopy at the right time in chronic gastritis cases. Today, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) parameters have been found to be useful in demonstrating inflammation. In our study, we aimed to investigate the relationship between HP and NLR and PLR.
METHODS: In patients who were found to have antral gastritis according to biopsies which were taken during the gastroscopy procedure at the Health Sciences University Haydarpaşa Numune Health Application and Research Center between on March 1, 2016 and March 1, 2019, HP presence and hemogram parameters were recorded. Patients with chronic or active inflammatory disease, taking regular medications, or antibiotics in the past 2 months were excluded from the study. IBM SPSS Statistics 22 for statistical analysis (SPSS IBM, Türkiye) programs was used. p<0.05 was considered as significant.
RESULTS: In the histopathological examination of a total of 271 cases, 135 (49.8%) patients with HP positivity were evaluated as study group, and 136 (50.2%) patients with negativity were evaluated as control group. In the study group, NLR was 1.86±0.51 and PLR was 118.58±32.18 and in the control group, NLR was 1.92±0.63 and PLR was 117.21±34.82. There was no statistically significant difference between the groups in terms of NLR and PLR (p>0.05).
DISCUSSION AND CONCLUSION: In predicting the presence of HP and deciding on endoscopy at the right time, prospective studies with larger numbers of cases and different parameters can contribute to clinicians.