Monocyte High-Density Lipoprotein Cholesterol Ratio and Coronary Collateral Circulation Development in Patients with Stable Coronary Artery Disease and no History of Revascularization
Sinan Varol, Fahrettin Katkat, Serkan Karahan, Irfan Şahin, Ertuğrul OkuyanDepartment of Cardiology, Bagcilar Training and Research Hospital, Istanbul, TürkiyeINTRODUCTION: In patients with chronic total occlusion (CTO), various degrees of coronary collateral circulation (CCC) can be seen. No clinical study was conducted for the relationship between monocyte/high-density lipoprotein cholesterol ratio (MHR) and the development of CCC.
METHODS: Among 17,391 patients, the angiographic procedures were analyzed. Patients who had a history of acute coronary syndrome, myocardial infarction, percutaneous coronary intervention (PCI), or coronary artery bypass graft (CABG) procedure were excluded from the study. A total of 217 patients with CTO were retrospectively analyzed. The Cohen-Rentrop classification was used for retrograde CCC score.
RESULTS: Both patient groups were male dominant. The prevalence of hypertension and diabetes was similar. MHR values did not differ between poor CCC versus good CCC groups (13.90±6.34 vs. 14.33±7.57, respectively, p=0.948). About 15.5% of patients in the poor CCC group and 19.9% of patients in the good CCC group have multiple CTOs.
DISCUSSION AND CONCLUSION: MHR as a novel marker of inflammation and atherosclerotic index is not related to CCC development in patients with CTO and stable coronary artery disease.
Manuscript Language: English