The Effect of Serum Cortisol and Vitamin D Levels on Mortality in Covid-19 Patients Admitted to the Intensive Care Unit
Uğur Uzun1, Murat Güneş2, Fatma Demet Arslan3, İsa Sahar1, Taner Çalışkan1, Çiler Zincircioğlu1, Kazım Rollas1, Nimet Şenoğlu4, Aykut Sarıtaş1, Işıl Köse11Department of Anesthesiology and Reanimation, University of Health Sciences Tepecik Training and Research Hospital, İzmir, Türkiye2Intensive Care Unit, State Hospital, Gümüşhane, Türkiye
3Department of Biochemistry, Bakırçay University Çiğli Training and Research Hospital, İzmir, Türkiye
4Department of Anesthesiology and Reanimation Bakırçay University Çiğli Training and Research Hospital, İzmir, Türkiye
INTRODUCTION: One of the ways to reduce deaths due to Coronavirus-19 disease is to identify the factors that increase the mortality of the disease. Deficiency of vitamin D, which supports the immune system, and corticosteroids administered to suppress excessive inflammatory response may be risk factors that may affect mortality.
METHODS: In our study, we evaluated serum vitamin D and cortisol levels in Covid-19 patients during their admission to the intensive care unit, together with the demographic data and comorbidities of the patients, and examined their effect on mortality and their relationship with intensive care unit (ICU) scoring systems.
RESULTS: In the study, 101 Covid-19 patients were examined. Serum vitamin D and cortisol levels did not affect mortality statistically. Intensive care unit admission was more common in patients with low vitamin D levels. Cortisol levels were also higher in patients who died.
DISCUSSION AND CONCLUSION: Vitamin D deficiency increased the risk of admission to the intensive care unit, and serum vita-min D and cortisol levels during admission to the intensive care unit had no effect on the prediction of mortality.
Manuscript Language: English