Factors Affecting Survival in Patients with Gastric Cancer Undergoing Surgery for Curative Purposes

INTRODUCTION: Gastric cancer is the fifth most common cancer today. It is the third most common cause of cancer-related death because it is usually at an advanced stage at the time of diagnosis. Several factors affect the prognosis of gastric cancer. In this study, we examined various factors affecting the prognosis in gastric cancer and evaluated their effects on the prognosis.
METHODS: Between 2011 and 2016, 146 patients who underwent resection with the diagnosis of curative gastric cancer in Haydarpaşa Numune Training and Research Hospital General Surgery Clinic were included in the study. A total of 146 gastric cancer patients who underwent curative surgery were retrospectively analyzed. Age, gender, type of operation, preoperative albumin and tumor markers, tumor stage, lymph node involvement, histological type, tumor localization, tumor differentiation, lymphovascular and perineural invasion, and Her-2 immunohistochemical features were examined, and survival analyses were performed.
RESULTS: Age, stage, lymph node involvement, and perineural-lymphovascular invasion were found to be statistically significant.
DISCUSSION AND CONCLUSION: It was concluded that the determination of these prognostic factors will have an important place in the planning of the treatment. However, the subject should be supported by randomized clinical studies involving more patients.