Leukocytoclastic Vasculitis and Renal Cell Carcinoma

Leukocytoclastic vasculitis (LCV) is the most common form of cutaneous vasculitis, which represents inflammation of small vessels in the skin stemming from immune complex deposition. The disease can affect several organs of the body, such as the kidneys, central nervous system, heart, gastrointestinal tract, and lungs, or it can be confined to only the skin. LCV clinically presents with an eruption of palpable purpuric papules, which may have central vesicles or pustules and may coalesce into larger plaques. LCV causative factors or associated diseases are usually drugs, infection, and rheumatic or collagen vascular disease but rarely malignancies. There are few studies on LCV associated with renal cell carcinoma (RCC). We report the case of our patient with LCV leading to the discovery of an asymptomatic, surgically curable RCC of the kidney.

Lökositoklastik Vaskülit ve Renal Hücreli Karsinom

Lökositoklastik vaskülit küçük damarlarýn inflamasyonu ile karakterize bir hastalýktýr. Etiyolojide ilaçlar, enfeksiyonlar, maligniteler, sistemik inflamatuvar hastalýklar gibi çeþitli nedenler yer almaktadýr. Ancak olgularýn bir kýsmýnda neden saptanamamakta ve bu olgular idiyopatik olarak deðerlendirilmektedir (1). Renal hücreli karsinom (RHK) ile iliþkili lökositoklastik vaskülit olgusu literatürde az sayýda bildirilmiþtir. Bu bildiride lökositoklastik vaskülit nedenleri araþtýrýlýrken RHK saptanýp baþarýlý bir þekilde cerrahi tedavi uygulanan hasta sunulmaktadýr.