Haydarpasa Numune Med J. 2021; 61(3): 341-345 | DOI: 10.14744/hnhj.2019.38233

The Clinical Significance of Neutrophil Lymphocyte Ratio, Monocyte Lymphocyte Ratio and Platelet Lymphocyte Ratio in Patients with Guillain-Barré Syndrome

Cihan Bedel, Mustafa Korkut
Health Sciences University, Antalya Training And Research Hospital, Department of Emergency Medicine, Antalya

INTRODUCTION: The purpose of this study was to determine the prognostic value of the pretreatment neutrophil lymphocyte ratio (NLR), and platelet lymphocyte ratio (PLR) and monocyte lymphocyte ratio (MLR) in the diagnosis of Guillain-Barré Syndrome (GBS).
METHODS: This retrospective study enrolled a total of 98 GBS patients and 101 healthy control (HC).
RESULTS: Our study showed that GBS patients had higher level of NLR,PLR and MLR compared with HC (p < 0.001, p < 0.001, p < 0.001, respectively). We investigated the effectiveness of NLR, PLR and MLR in prediction of GBS using receiver operating characteristic (ROC) analysis. NLR had the highest area under curve (AUC) (0.912, 95% CI, 0.870 to 0.954), followed by MLR and PLR (AUC = 0.811, 0.753, respectively).
DISCUSSION AND CONCLUSION: NLR, PLR and MLR can be considered as a potential inflammatory biomarker for GBS patients

Keywords: Guillain-Barré syndrome, monocyte lymphocyte ratio, neutrophil lymphocyte ratio, platelet lymphocyte ratio,

---

Guillain-Barré Sendromlu Hastalarda Nötrofil Lenfosit Oraný, Monosit Lenfosit Oraný ve Trombosit Lenfosit Oranýnýn Klinik Önemi

Cihan Bedel, Mustafa Korkut
Saðlýk Bilimleri Üniversitesi Antalya Eðitim Ve Araþtýrma Hastanesi,Acil Týp Ana Bilim Dalý,Antalya

GÝRÝÞ ve AMAÇ: Bu çalýþmanýn amacý Guillain-Barré Sendromu (GBS) tanýsýnda tedavi öncesi nötrofil lenfosit oraný (NLR) ve trombosit lenfosit oraný (PLR) ve monosit lenfosit oraný (MLR) 'nýn prognostik deðerini belirlemekti.
YÖNTEM ve GEREÇLER: Bu retrospektif çalýþmada toplam 98 GBS hastasý ve 101 saðlýklý kontrol (HC) vardý.
BULGULAR: Çalýþmamýz GBS hastalarýnda HC ile karþýlaþtýrýldýðýnda daha yüksek düzeyde NLR, PLR ve MLR olduðunu gösterdi (sýrasýyla p <0.001, p <0.001, p <0.001). Alýcý iþletim karakteristiði analizini (ROC) kullanarak NLR, PLR ve MLR'nin GBS hastalýðý tahminindeki etkinliðini araþtýrdýk. NLR eðri altýndaki en yüksek alana (AUC) sahipti (0.912,% 95 CI, 0.870 ila 0.954), ardýndan MLR ve PLR (sýrasýyla AUC = 0.811, 0.753) gelmekteydi.
TARTIÞMA ve SONUÇ: NLR, PLR ve MLR, GBS hastalarý için potansiyel bir inflamatuar biyobelirteç olarak düþünülebilir.

Anahtar Kelimeler: Guillain-Barré sendromu, monosit lenfosit oraný, nötrofil lenfosit oraný, trombosit lenfosit oraný,

---

CITE