Factors Affecting Survival in Patients with Acute Kidney Injury and Receiving Renal Replacement Therapy

INTRODUCTION: Acute kidney injury (AKI) is a common problem. This study aimed to compare the results of complete recovery, chronic kidney disease (CKD), end-stage renal disease (ESRD), and death in patients receiving renal replacement therapy (RRT) by examining the factors determining mortality and morbidity in patients with AKI.
METHODS: Patients who received RRT due to AKI in our hospital between 2012 and 2013 were analyzed retrospectively. Eighty-seven patients diagnosed with AKI according to RIFLE and KDIGO criteria and who received RRT were evaluated according to their demographic, laboratory, and recovery status.
RESULTS: The number of patients undergoing hemodialysis due to AKI was 87. Forty-four of the cases were female, and 43 were male. The mean age was 67.6±17 years. Eighty-one of the patients had at least one co-morbid disease other than AKI. Thirty-one patients died before leaving the hospital. Nineteen patients recovered from AKI. Permanent kidney damage occurred in 37 patients. Two patients developed ESRD. The most common cause of death was sepsis (39%).
DISCUSSION AND CONCLUSION: According to RIFLE and KDIGO classification, in patients with AKI who underwent RRT, the presence of infection, concomitant diseases, and advanced age of the patient significantly contribute to determining the prognosis when examining the irreversible deterioration of kidney functions and the factors causing the death of the patient.