ISSN: 2630-5720 | E-ISSN: 2687-346X
Diagnostic Value of Contrast-Enhanced Vessel Wall Imaging in the Evaluation of Various Intracranial Non-Vascular Pathologies: A Single Center Experience [Haydarpasa Numune Med J]
Haydarpasa Numune Med J. 2024; 64(2): 241-247 | DOI: 10.14744/hnhj.2022.71542

Diagnostic Value of Contrast-Enhanced Vessel Wall Imaging in the Evaluation of Various Intracranial Non-Vascular Pathologies: A Single Center Experience

Deniz Aliş1, Düzgün Yıldırım2, Amalya Zeynalova2, Filiz Tüzüner3, Mustafa Emir Tavşanlı4, Mustafa Seçkin4, Elvan Cevizci Akkılıç5, Murat Hamit Aytar6, Deniz Esin Tekcan Şanlı7
1Department of Radiology, Acibadem Maslak Hospital, Istanbul, Türkiye
2Department of Radiology, Acibadem Taksim Hospital, Istanbul, Türkiye
3Department of Neurology, Acibadem Taksim Hospital, Istanbul, Türkiye
4Department of Anesthesiology, Acibadem Taksim Hospital, Istanbul, Türkiye
5Department of Neurology, Acibadem Kozyatagi Hospital, Istanbul, Türkiye
6Department of Radiology, Acibadem Kozyatagi Hospital, Istanbul, Türkiye
7Department of Neurosurgery, Acibadem Kozyatagi Hospital, Istanbul, Türkiye

INTRODUCTION: Vessel Wall Imaging (VWI) is a relatively novel magnetic resonance imaging (MRI) technique primarily aimed at diagnosing vascular pathologies. In this study, we aimed to evaluate the diagnostic value of contrast-enhanced (CE) VWI in identifying various intracranial non-vascular pathologies.
METHODS: This retrospective study was approved by our institutional ethics committee with approval number 2022-05/17 on March 11, 2022. We retrospectively evaluated cranial CE-MRI, including the VWI sequence, of 189 patients (76 females and 113 males) who were referred to our radiology department for brain imaging for various reasons. MRI examinations were performed using a 3 Tesla unit. A single observer evaluated anonymized cranial MRI images without CE-VWI in addition to the relevant clinical information in a random order. The same observer interpreted the CE-VWI with relevant clinical information six weeks later. The findings, which could only be visualized on VWI in the second session, were noted.
RESULTS: In 10 patients of our study cohort (5.3%), VWI demonstrated pathological signal alterations or contrast enhancement (e.g., post-status frontal lobe pial enhancement in a patient with autoimmune epilepsy, contrast enhancement in the hippocampus in a diffusion-negative hyper-acute ischemic stroke patient, and optic disc enhancement in a patient with intracranial hypertension) that apparently reflected underlying clinical disorders, which otherwise could not be visualized on conventional MRI.
DISCUSSION AND CONCLUSION: CE-VWI might serve as a valuable adjunct for the diagnosis of various parenchymal or meningeal intracranial diseases, yet further, more comprehensive studies are needed to reveal the true potential of VWI.

Keywords: FLAIR, Intracranial Parenchymal Diseases, MRI, Vessel Wall Imaging.

Deniz Aliş, Düzgün Yıldırım, Amalya Zeynalova, Filiz Tüzüner, Mustafa Emir Tavşanlı, Mustafa Seçkin, Elvan Cevizci Akkılıç, Murat Hamit Aytar, Deniz Esin Tekcan Şanlı. Diagnostic Value of Contrast-Enhanced Vessel Wall Imaging in the Evaluation of Various Intracranial Non-Vascular Pathologies: A Single Center Experience. Haydarpasa Numune Med J. 2024; 64(2): 241-247

Corresponding Author: Amalya Zeynalova, Türkiye
Manuscript Language: English
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