ISSN: 2630-5720 | E-ISSN: 2687-346X
Ultrasonographic Features Predictive of Malignancy in Intraductal Papillary Neoplasm of the Breast [Haydarpasa Numune Med J]
Haydarpasa Numune Med J. 2024; 64(2): 248-253 | DOI: 10.14744/hnhj.2024.93708

Ultrasonographic Features Predictive of Malignancy in Intraductal Papillary Neoplasm of the Breast

İsmail Yurtsever1, Şeyma Yıldız1, Abdusselim Adil Peker1, Hafize Otçu Temur1, Bahar Atasoy1, Serdar Balsak1, Özlem Toluk2
1Department of Radiology, Bezmialem Vakıf University, İstanbul, Türkiye
2Department of Bioistatistics, Bezmialem Vakıf University, İstanbul, Türkiye

INTRODUCTION: To detect and evaluate features of gray scale B-mode ultrasonographic examination findings that may predict malignancy in intraductal lesions of the breast.
METHODS: In this retrospective study, 650 cases examined at Bezmialem Vakıf University Department of Radiology between January 2018 and December 2019 were scanned. Fifty-two female cases who were diagnosed with intraductal papillary lesions on gray scale B-mode US examination and underwent core biopsy were included.
RESULTS: Lesions were evaluated according to their largest size (4-50 mm, median 13 mm); the largest size of the lesion was found to be higher in the malignant group than in the benign group (p=0.008). As a result of our ROC analysis in terms of predicting benign and malignant outcomes with the largest size of the lesion, AUC=0.764, sensitivity 81.8%, specificity 70.7%, and cut-off>10.5 mm (p=0.001). According to this result, lesions over 10.5 mm are more likely to be malignant.
DISCUSSION AND CONCLUSION: There is a lot of benign/malignant overlap in the radiological features of papillary lesions. We found the lesion size to be the most important feature in this distinction. Therefore, in cases that warrant suspicion, performing a core needle biopsy may be indispensable.

Keywords: Breast cancer, breast papillary neoplasm, core needle biopsy, ductal carcinoma in situ, papilloma.

İsmail Yurtsever, Şeyma Yıldız, Abdusselim Adil Peker, Hafize Otçu Temur, Bahar Atasoy, Serdar Balsak, Özlem Toluk. Ultrasonographic Features Predictive of Malignancy in Intraductal Papillary Neoplasm of the Breast. Haydarpasa Numune Med J. 2024; 64(2): 248-253

Corresponding Author: İsmail Yurtsever, Türkiye
Manuscript Language: English
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