Haydarpasa Numune Med J. 2019; 59(1): 78-83 | DOI: 10.14744/hnhj.2018.93723

Sleep Quality and Restless Legs Syndrome in Patients with Ankylosing Spondylitis

Gülbün Asuman Yüksel¹, Duygu Kurtuluþ², Hülya Tireli^1
1Department of Neurology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
²Department of Physical Medicine and Rehabilitation, Umraniye Training and Research Hospital, Istanbul, Turkey

INTRODUCTION: We aimed to investigate restless leg syndrome (RLS) prevalence and sleep quality in patients with ankylosing spondylitis (AS) and to explore the association between RLS and measures of disease activity and physical function in AS.
METHODS: Twenty (5 female, 15 male) consecutive patients with AS and 20 (5 female, 15 male) healthy volunteers were enrolled in this study. RLS was diagnosed by International Restless Legs Syndrome Study Group (IRLSSG-2003). Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), where scores >5 indicated poor sleep quality.
RESULTS: Prevalence of RLS was 55% (11 patients) in patients with AS. The mean RLS disability value was 21 (SD, 7.9). The modified Schober test levels were significantly higher (p=0.011) and Bath Ankylosing Spondylitis Functional Index (BASFI) scores were significantly lower (p=0.016) in the RLS group than in the non-RLS group. The Bath AS Disease Activity Index (BASDAI) scores were lower in the RLS group than in the non-RLS group, but the difference was not statistically significant (p=0.16). Sleep quality was poor in 12 patients [PSQI score=7.09 (SD, 3.67)].
DISCUSSION AND CONCLUSION: We emphasized that it is important to determine the existence of RLS and poor sleep quality in patients with AS. However, further examination by applying the diagnostic criteria for RLS and PSQI in more number of patients with AS will be useful.

Keywords: Ankylosing spondylitis, restless legs syndrome; sleep quality.

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Ankilozan spondilit hastalarýnda uyku kalitesi ve huzursuz bacak sendromu

Gülbün Asuman Yüksel¹, Duygu Kurtuluþ², Hülya Tireli^1
1Haydarpaþa Numune Eðitim Ve Araþtýrma Hastanesi Nöroloji Kliniði, Ýstanbul
²Ümraniye Eðitim Ve Araþtýrme Hastanesi; Fizik Tedavi Ve Rehabilitasyon Kliniði, Ýstanbul

GÝRÝÞ ve AMAÇ: Biz bu çalýþmada Ankilozan spondilit (AS) hastalarýnda huzursuz bacak prevalansýný ve uyku kalitesininin bozulup bozulmadýðýný ve ayrýca hastalýk aktivitesi ve hastalarýn fiziksel fonksiyon durumu ile HBS arasýnda bir iliþki olup olmadýðýný görmeyi amaçladýk.
YÖNTEM ve GEREÇLER: Çalýþmaya 20 AS hastasý (15 E, 5K) ve kontrol grubu olarak 20 saðlýklý birey (15 E, 5K) alýndý. HBS tanýsý, Uluslararasý Huzursuz Bacak Sendromu Çalýþma Grubu’nun 2003 yýlýnda yayýnladýðý HBS taný kriterlerine (IRLSSG-2003) göre konuldu. Uyku kalitesi, Pittsburgh Uyku Kalite Ýndeksi (PSQI) ile deðerlendirildi ve >5 puan bozulmuþ uyku kalitesi olarak alýndý.
BULGULAR: AS hastalarýnýn 11’inde(%55) HBS saptandý. Ortalama HBS dizabilite deðeri 21 (SD: 7.9). HBS olmayan AS hastalarý ile karþýlaþtýrýldýðýnda, HBS olan AS hastalarýnda Modified Schober deðerleri anlamlý yüksek (p=0.011) ve Bath AS fonksiyon indeksi (BASFI) skorlarý anlamlý düþük bulundu (p=0.016). Bath AS hastalýk aktivite indeks (BASDAI) skorlarý da HBS olan grupta daha düþük olmasýna raðmen istatiksel olarak anlamlý fark saptanmadý (p=0.16). Uyku kalitesi 12 hastada bozuk bulundu [PSQI=7.09 (SD: 3.67)].
TARTIÞMA ve SONUÇ: AS hastalarýnda HBS mevcudiyetini ve uyku kalitesinin bozulup bozulmadýðýný belirlemek önemli olabilir. Bu nedenle daha fazla sayýda AS hastasý içeren çalýþmalar ile AS hastalarýnda HBS mevcudiyeti ve uyku kalitesinin bozulup bozulmadýðýnýn belirlenmesi düþünülebilir.

Anahtar Kelimeler: Ankilozan spondilit, huzursuz bacak sendromu, uyku kalitesi

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