INTRODUCTION: We aimed to define the compatibility between biopsy and surgical pathology results in connection with age, prostate-specific antigen (PSA), prostate volume (PV), and body mass ındex (BMI) in prostate cancer (PCa) patients. PCa is the second most common male cancer in the world. PCa is also the most common urological cancer and is the second most common cancer after lung cancer among all cancers in Türkiye.
METHODS: We evaluated 165 PCa patients who were diagnosed with ultrasound-guided transrectal-targeted prostate biopsy and then operated with open radical prostatectomy. We compared the Gleason Scores (GSs) of biopsy specimens and the GSs of the prostatectomy specimens with the relationship of some parameters as age, PSA, PV, and BMI.
RESULTS: Pathology data were at similar compatibility ratio (67%) in both groups < 65 and ≥ 65-year-old Pathology results were consistent in patients with a PSA value <10 ng/mL and ≥10 ng/mL as 66% and 73%, respectively. The histopathological compliance in patients with a PV <80 cc and ≥80 cc was 66% and 93%, respectively. The compatibility of BMI with the pathology results was found at the group with BMI ≥25 kg/cm² (64%) and the patients with BMI <25 kg/cm² (74%).
DISCUSSION AND CONCLUSION: The harmony between the fine needle biopsies and the radical prostatectomy specimens GS varies between 24% and 78% in the literature. When all patients were taken into consideration, a moderate agreement was found between the pathology results of biopsy and the pathology results of surgery (110/165, 67%).