If you Want to Find, you Must Think: Case Report and Literature Review of the Periprosthetic Knee Infection from Brucella Melitensis

In addition to the difficulty of diagnosis in periprosthetic joint infections (PJI) following total knee arthroplasty, the infectious agent is also often difficult to identify. Correct identification of the pathogen increases the chance of a successful treatment. Although rare, clinicians should keep Brucella infections in mind when a pathogen cannot be found in PJI cases. A 58-year-old female patient was diagnosed with a periprosthetic Brucella infection following bilateral total knee arthroplasty. All symptoms disappeared in the postoperative 1st year after a two-step revision arthroplasty. We aimed to draw attention to periprosthetic infections caused by Brucella and to perform a review of literature in this case report.